When dealing with algorithm penalties:

A site can be affected by multiple updates at once, but more severe penalties will override smaller penalties
One site can only be affected by one update at a time
A site can be affected by multiple updates, but only if they occur near each other
A site can be affected by more than one update, but no more than two at once
All of the mentioned options are true
A site can be affected by multiple updates from multiple time periods if issues are left uncorrected

The correct answer is:

A site can be affected by multiple updates from multiple time periods if issues are left uncorrected.